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DNA Delivery System Triples CRISPR’s Efficiency
Researchers have unveiled a new type of nanostructure that dramatically improves CRISPR delivery. Called lipid nanoparticle spherical nucleic acids, these tiny structures carry the full set of CRISPR editing tools in a protective DNA shell.

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Novel ENPP1-Blocking Drug Heats Up Cold Solid Tumors
Researchers develop immunotherapy drug STF-1623, which safely prevents cancer cells from hiding from the immune system’s first responders

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Scientists Transform Plastic Waste Into Efficient CO2 Capture Materials
Researchers have developed a method to convert plastic waste into a climate solution for efficient and sustainable CO2 capture, tackling two major environmental challenges at once.

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Delayed Breakfast Linked to Higher Mortality in Older Adults
Researchers studied changes to meal timing in older adults and discovered that people experience gradual shifts in when they eat meals as they age. They also found specific trajectories linked to an earlier death.

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Dual Impact Target Halts Glioblastoma Growth and Immune Evasion
Researchers have discovered a drug target in glioblastoma cells that could potentially undermine both these sources of resistance.

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Decades of Beta Blocker Use Questioned as Major Study Shows No Benefit
The REBOOT trial, spanning 8,438 patients across 109 hospitals, found beta blockers offered no benefit after heart attack in patients with preserved or mildly reduced heart function. Women faced higher risks, particularly at higher doses.

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Mucus Microspheres Offer Controlled Drug Delivery and Convenient Lubrication
Researchers have developed mucus and polydopamine-based microspheres that offer controlled drug release and biological adaptability, with the added bonus of easy lubrication.

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Reprogrammed Biocatalysts Generate a Library of Novel Drug Molecules
Researchers have detailed an enzymatic multicomponent reaction, resulting in six distinct molecular scaffolds, many of which were not previously accessible by other chemical or biological methods.

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Humans and AI Blend Two Types of Learning
Brown University researchers found that humans and AI integrate two types of learning – fast, flexible learning and slower, incremental learning – in surprisingly similar ways. The study revealed trade-offs between memory retention and flexibility.

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New Polymer Paves the Way for Recyclable Water-Based Batteries
Researchers have developed a new organic redox polymer that can be used as the active material in battery electrodes, and that breaks down for easy recycling under mild conditions.
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