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Hormone Combination Improves Strength in FSHD Patients
A study has found that a combined regimen of growth hormone and testosterone is safe, well-tolerated and is associated with meaningful improvements in muscle mass, strength and mobility for men living with facioscapulohumeral muscular dystrophy.

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GLP-1 Drugs Pose Pregnancy Risks – 79% of Women Not Using Protection
A new study has revealed that most Australian women of reproductive age prescribed GLP-1 receptor agonists are not using effective contraception, despite known risks during pregnancy.

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Aspirin Therapy Ineffective in Treating Chronic Rhinosinusitis With Nasal Polyps
A randomised placebo-controlled study showed that aspirin therapy does not provide significant relief for people suffering from chronic rhinosinusitis with nasal polyps who are hypersensitive to non-steroidal anti-inflammatory drugs (NSAIDs).

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A "Three-Tailed" Fat Helps Cells Survive Heart Attacks
Scientists discovered that NAPE, a “three-tailed” fat molecule, helps protect cells during oxygen loss caused by stroke or heart attack. NAPE surges under stress, boosting lactic acid export and preventing toxic buildup.

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Repurposed Industrial Dyes Offer Clues to Distinguish Dementia Types
UC San Francisco researchers screened 300 industrial dyes to identify those that bind to protein clumps linked to dementias like Alzheimer’s. They found 10 promising candidates, including one that illuminated tau in brain samples.

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First Broad-Spectrum Antiviral Shows Promise Against Multiple Viruses
A new study offers a promising path toward the development of the world’s first broad-spectrum antiviral, which could be deployed against a wide range of deadly viruses, including future pandemic threats.

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Blood Biomarker Study Reveals Underrepresentation in Alzheimer’s Trials
Some populations with the highest risk for Alzheimer’s disease remain greatly underrepresented in clinical trials. Participants from these high-risk groups are less likely to have elevated amyloid in the brain based on blood levels of p-tau217.

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Decades of Beta Blocker Use Questioned as Major Study Shows No Benefit
The REBOOT trial, spanning 8,438 patients across 109 hospitals, found beta blockers offered no benefit after heart attack in patients with preserved or mildly reduced heart function. Women faced higher risks, particularly at higher doses.

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Mucus Microspheres Offer Controlled Drug Delivery and Convenient Lubrication
Researchers have developed mucus and polydopamine-based microspheres that offer controlled drug release and biological adaptability, with the added bonus of easy lubrication.

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Reprogrammed Biocatalysts Generate a Library of Novel Drug Molecules
Researchers have detailed an enzymatic multicomponent reaction, resulting in six distinct molecular scaffolds, many of which were not previously accessible by other chemical or biological methods.
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