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Latest App Notes & Case Studies

Microscopic view of multiplying cancer cells in a dark fluid environment.
App Note / Case Study

Optimize CAR-T Cell Manufacturing Efficiency

This application note explores how advanced SFM formulations can dramatically improve CRISPR-modified CAR-T cell production while maintaining GMP compliance and scalability.
Agilent report on TGF-β activity in angiogenesis research.
App Note / Case Study

High-Throughput, Quantitative Evaluation of TGF-β Signaling in Angiogenesis

This application note highlights how combining a phosphorylation and translocation assay with a confocal imaging reader can provide a robust and sophisticated method for analyzing the magnitude of SMAD activation. This in turn provides quantitative e
Agilent research paper on cAMP analysis with cADDis biosensor and live-cell imaging results
App Note / Case Study

Real-Time cAMP Analysis With cADDis Biosensor and Automated Live-Cell Imaging

This application note explores how, when coupled with live-cell imaging, these tools can offer improved sensitivity, faster turnaround and greater detail for Gs- and Gi- pathway monitoring.
Gloved hand holding microcentrifuge tube in front of spectrophotometer data on lab computer screen
App Note / Case Study

Revolutionize Oligonucleotide Bioanalysis Using Automated SPE

This application note demonstrates how an integrated automated SPE workstation combined with next-generation triple quadrupole liquid chromatography–mass spectrometry (LC/MS) technology delivers superior sensitivity, reproducibility and efficiency fo
Scientist in lab coat and gloves performing maintenance on HPLC system in laboratory
App Note / Case Study

Choosing the Right SEC Column for Oligonucleotide Separation

This application note provides expert guidance on choosing the right SEC columns and optimizing method conditions to achieve reliable oligonucleotide separations.
A person wearing blue gloves places small vials into a blue sample holder in a laboratory, with scientific equipment visible in the background.
App Note / Case Study

Streamline Antisense Oligonucleotide QC With Robust LC/MS Purity Assessment

This application note demonstrates how advanced unit mass detection technology can deliver the sensitivity and selectivity required for comprehensive purity assessment, enabling routine testing labs to implement a more practical and robust analytical
Female scientist placing sample tubes into an automated lab analyzer in a modern laboratory.
App Note / Case Study

Streamline High-Throughput Oligonucleotide Analysis With Ion-Pairing-Free Methods

This application note demonstrates how an ammonium bicarbonate-based approach eliminates bottlenecks while maintaining excellent chromatographic performance and mass spectrometry sensitivity.
Abstract glowing orange DNA double helix with connected nodes on a dark network background
App Note / Case Study

Optimize Oligonucleotide Analysis With Advanced Chromatography Methods

This application note reveals how hydrophilic interaction chromatography (HILIC) provides a versatile, MS-compatible alternative that delivers superior separation performance without the limitations of conventional approaches.
Doctor providing supportive HPV consultation to a concerned patient in a clinical setting.
App Note / Case Study

Potential Expansion of HPV Screening With First-Void Urine Self-Sampling

This app note examines breakthrough approaches to first-void urine collection and preservation, highlighting their analytical performance, user accessibility and compatibility with today's molecular diagnostic platforms.
Colorful 3D representation of DNA base pairs used in next-generation sequencing analysis
App Note / Case Study

Overcome RNA-Seq Challenges With Adaptive Focused Acoustics Technology

This application note explores the latest advanced acoustic fragmentation technology, which delivers consistent, high-quality results from even the most challenging clinical specimens.

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